BPL1® is a clinically studied postbiotic derived from the probiotic strain Bifidobacterium animalis CECT 8145. It contains beneficial bioactive compounds produced during fermentation and is shown in clinical research to support reductions in belly fat, visceral fat, and promote metabolic health. BPL1® is also rich in lipoteichoic acid—a key compound studied for its role in supporting fat metabolism and GLP-1–associated appetite and metabolic pathways.*

Scientifically
Studied Benefits of BPL1®

Human and preclinical studies on BPL1® HT (heat-treated Bifidobacterium animalis subsp. lactis CECT 8145) show support for:

• Fat Metabolism & Abdominal Fat:
  Shown in a clinical trial to support reductions in belly fat and visceral fat in adults with abdominal obesity (Pedret et al., 2019).
• Metabolic Health:
  Supports healthy insulin sensitivity and metabolic function (Pedret et al., 2019; Balaguer et al., 2022).
• Cardiovascular Support:
  May help support healthy lipid metabolism and visceral fat reduction (Pedret et al., 2019).
• Gut & Digestive Health:
  Contributes to microbial balance and gut barrier support (Caimari et al., 2017).
• Immune Support:
  Helps support immune balance and a healthy inflammatory response (Caimari et al., 2017).
• Recovery & Athletic Support:
  May aid post-exercise recovery and energy metabolism by supporting fat utilization and inflammatory balance (Caimari et al., 2017).
• Mood & Cognitive Balance:
  Preclinical evidence suggests a role in gut-brain axis support and emotional health (Balaguer et al., 2022).
• Skin Health:
  May support skin clarity through gut-skin axis modulation (Caimari et al., 2017; Salem et al., 2018).
• Nutrient Absorption:
  May contribute to improved nutrient absorption by supporting gut barrier integrity (Caimari et al., 2017).

Select References:

• Pedret, A., Valls, R. M., Calderón-Pérez, L., et al. (2019). Effects of daily consumption of the probiotic Bifidobacterium animalis subsp. lactis BPL1 on abdominal adiposity in adults with abdominal obesity: a randomized controlled trial. International Journal of Obesity, 43(9), 1863–1868.
• Caimari, A., del Bas, J. M., Boqué, N., et al. (2017). Heat-killed Bifidobacterium animalis subsp. lactis CECT 8145 influences lipid metabolism and adiposity in metabolic syndrome. Journal of Functional Foods, 35, 126–136.
• Balaguer, F., Enrique, M., Llopis, S., Barrena, M., Navarro, V., Álvarez, B., & Chenoll, E. (2022). Lipoteichoic acid from Bifidobacterium animalis subsp. lactis BPL1: a novel postbiotic that reduces fat deposition via IGF-1 pathway. Microbial Biotechnology, 15(3), 805–816.
• Salem, I., Ramser, A., Isham, N., & Ghannoum, M. A. (2018). The gut microbiome as regulator of the gut-skin axis. Frontiers in Microbiology, 9, 1459.

DE111® is a highly researched, proprietary strain of Bacillus subtilis known for its resilience and rapid action. Its spore-forming structure helps it survive harsh gastrointestinal conditions, enabling metabolic activity in the gut. Clinical studies have shown that DE111® supports digestion, immune function, and metabolic health.*

Recent research (Colom et al., 2023) demonstrates that DE111® begins delivering measurable physiological support within just 4 hours of ingestion, including increases in antioxidant levels and compounds associated with a healthy inflammatory response. It also supports the production of proteins linked to digestive and immune system function.*

Scientifically Studied Health Benefits of DE111®

• Fast-acting physiological support:
  Within just 4 hours of ingestion, DE111® has been shown to increase markers associated with antioxidant activity, metabolic support, and inflammatory balance. It also influences proteins linked to immune and digestive function, suggesting early support for gut and metabolic health (Colom et al., 2023).
• Digestive health support:
  Helps support gut microbiota balance, promotes regularity, and may alleviate occasional constipation or diarrhea (Cuentas et al., 2021).
• Weight management:
  May support healthy weight management by modulating gut microbiota composition and metabolic processes (Cani et al., 2009).
• Antimicrobial activity:
  Exhibits antimicrobial activity in vitro by inhibiting the growth of certain opportunistic gut bacteria (Mazhar et al., 2023).
• Immune function:
  Supports immune health by modulating immune markers and promoting gut barrier function (Freedman et al., 2021).
• Cardiovascular support:
  May support healthy blood lipid levels, including total and non-HDL cholesterol, contributing to cardiovascular wellness (Trotter et al., 2020).
• Athletic recovery & body composition:
  Shown to support muscle recovery and favorable body composition when combined with exercise and may influence markers of inflammation and performance (Townsend et al., 2018).
• Metabolic health:
  Supports metabolic wellness by helping maintain healthy cholesterol, glucose, and triglyceride levels (ADM, 2023).
• Inflammatory balance:
  Contributes to a healthy inflammatory response in the gut and systemically (Freedman et al., 2021).
• Nutrient absorption:
  May enhance nutrient absorption by supporting gut microbiota balance and intestinal function (ADM, 2023).
• Gut colonization:
  Demonstrates strong adhesion to intestinal epithelial cells in vitro, which may support stable gut colonization and probiotic activity (Mazhar et al., 2023).
• Gut barrier integrity:
  Supports gut barrier integrity, a key factor in maintaining digestive and immune health (Mazhar et al., 2023).
• Skin health:
  May support healthy skin through gut-skin axis modulation (Salem et al., 2018).
• Mood & cognitive function:
  May support mood, emotional balance, and cognitive function through gut-brain axis signaling (Berding et al., 2021).
  

Select References:

• ADM (2023). Bacillus subtilis DE111®: Metabolic and Digestive Health Benefits. ADM Product Information Sheet.
• Berding, K., Long-Smith, C. M., & Cryan, J. F. (2021). The microbiota-gut-brain axis in brain health and disease. Frontiers in Psychiatry, 12, 606634.
• Cani, P. D., et al. (2009). Gut microbiota fermentation of prebiotics influences appetite and glucose metabolism. The American Journal of Clinical Nutrition, 90(5), 1236–1243.
• Colom, J., et al. (2023). Acute physiological effects following Bacillus subtilis DE111 oral ingestion – a randomized, double-blinded, placebo-controlled study. Beneficial Microbes, 14(1), 17–29.
• Cuentas, A. M., et al. (2021). Gastrointestinal and immunomodulatory effects of DE111®. Journal of Probiotics & Health, 9(1), 1–7.
• Freedman, K. E., et al. (2021). Gastrointestinal and immunomodulatory effects of Bacillus subtilis DE111®. International Journal of Molecular Sciences, 22(5), 2453.
• Mazhar, S., Khokhlova, E., Colom, J., Simon, A., Deaton, J., & Rea, K. (2023). In vitro and in silico assessment of probiotic and functional properties of Bacillus subtilis DE111®. Frontiers in Microbiology, 12, Article 1101144.
• Salem, I., Ramser, A., Isham, N., & Ghannoum, M. A. (2018). The gut microbiome as regulator of the gut-skin axis. Frontiers in Microbiology, 9, 1459.
• Townsend, J. R., et al.
  (2018). Effects of DE111 probiotic on body composition and performance in
  collegiate athletes. Journal of Strength and Conditioning Research,
  32(7), 1929–1934.
• Trotter, R. E., Vazquez, A. R., Grubb, D. S., Freedman, K. E., & Weir, T. L. (2020). Bacillus subtilis DE111 intake may improve blood lipids and endothelial function. Beneficial Microbes, 11(7), 621–630.

Fructooligosaccharides (FOS) are natural prebiotic fibers derived from chicory root that selectively nourish beneficial gut bacteria, promoting microbiome balance and digestive health. By enhancing fermentation in the gut, FOS supports the production of beneficial short-chain fatty acids (SCFAs), which help maintain digestive comfort and are associated with gut hormone pathways like GLP-1 to support overall wellness.*

Scientifically Studied Health Benefits of FOS

• Digestive Health:
  Promotes beneficial gut bacteria, supports gut barrier function, increases stool bulk, and may help relieve occasional constipation and digestive discomfort (Slavin, 2013; Gibson et al., 2004; Shang et al., 2020; Topping & Clifton, 2001).
• Immune Function:
  Supports immune health through its influence on gut microbiota and gut-associated lymphoid tissue (Macfarlane et al., 2006; Lomax & Calder, 2009).
• Weight Management:
  May support appetite regulation and metabolic health by influencing gut hormones such as GLP-1 and peptide YY (Cani et al., 2009; Parnell & Reimer, 2009).
• Brain & Mood Health:
  May help support emotional well-being and cognitive function via the gut-brain axis and increased SCFA production (Smith et al., 2015; Berding et al., 2021).
• Skin Health:
  May support skin health indirectly through effects on gut barrier integrity, microbiota balance, and immune signaling (Salem et al., 2018).
• Cardiovascular Health:
  May support cardiovascular health by positively influencing cholesterol metabolism, glucose regulation, and inflammatory balance (Brighenti, 2007; Dehghan et al., 2014).
• Athletic Recovery:
  May support nutrient absorption (e.g., calcium and magnesium), gut balance, and immune function — factors that contribute to physical recovery and performance (Scholz-Ahrens et al., 2007; Cox et al., 2010).
• Colorectal Health:
  Associated with improved microbiota composition and SCFA production, which may play a protective role in colon health (Pool-Zobel et al., 2005).
• Gastrointestinal Comfort (including IBS):
  At low doses, may support gut function and digestive comfort in sensitive individuals by improving microbiota balance and fermentation patterns (Wilson & Whelan, 2017).
• Oral Health:
  May help support oral microbiome balance and reduce plaque-forming bacteria (Gupta et al., 2020).
   

Select References:

• Berding, K., Long-Smith, C. M., & Cryan, J. F. (2021). The microbiota-gut-brain axis in brain health and disease. Frontiers in Psychiatry, 12, 606634.
• Brighenti, F. (2007). Dietary fructans and serum triacylglycerols: a meta-analysis of randomized controlled trials. The Journal of Nutrition, 137(11 Suppl), 2552S–2556S.
• Cani, P. D., Lecourt, E., Dewulf, E. M., Sohet, F. M., Pachikian, B. D., Naslain, D., ... & Delzenne, N. M. (2009). Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal. The American Journal of Clinical Nutrition, 90(5), 1236–1243.
• Cox, A. J., Pyne, D. B., Saunders, P. U., & Fricker, P. A. (2010). Oral administration of the probiotic Lactobacillus fermentum VRI-003 and mucosal immunity in endurance athletes. British Journal of Sports Medicine, 44(4), 222–226.
• Dehghan, P., Gargari, B. P., & Jafar-Abadi, M. A. (2014). Oligofructose-enriched inulin improves some inflammatory markers and metabolic endotoxemia in women with type 2 diabetes mellitus: a randomized controlled clinical trial. Nutrition, 30(4), 418–423.
• Gibson, G. R., Probert, H. M., Van Loo, J., Rastall, R. A., & Roberfroid, M. B. (2004). Dietary modulation of the human colonic microbiota: updating the concept of prebiotics. Nutrition Research Reviews, 17(2), 259–275.
• Gupta, P., Gupta, N., Pawar, A. P., Birajdar, S. S., Natt, A. S., & Singh, H. P. (2020). Role of sugar and sugar substitutes in dental caries: A review. ISRN Dentistry, Article ID 5194210.
• Lomax, A. R., & Calder, P. C. (2009). Prebiotics, immune function, infection and inflammation: a review of the evidence. British Journal of Nutrition, 101(5), 633–658.
• Macfarlane, S., Macfarlane, G. T., & Cummings, J. H. (2006). Review article: prebiotics in the gastrointestinal tract. Alimentary Pharmacology & Therapeutics, 24(5), 701–714.
• Parnell, J. A., & Reimer, R. A. (2009). Weight loss during oligofructose supplementation is associated with decreased ghrelin and increased peptide YY in overweight and obese adults. The American Journal of Clinical Nutrition, 89(6), 1751–1759.
• Pool-Zobel, B. L., & Sauer, J. (2005). Overview of experimental data on reduction of colorectal cancer risk by inulin-type fructans. British Journal of Nutrition, 93(S1), S73–S90.
• Salem, I., Ramser, A., Isham, N., & Ghannoum, M. A. (2018). The gut microbiome as a major regulator of the gut-skin axis. Frontiers in Microbiology, 9, 1459.
• Scholz-Ahrens, K. E., Ade, P., Marten, B., Weber, P., Timm, W., Açil, Y., ... & Schrezenmeir, J. (2007). Prebiotics, probiotics, and synbiotics affect mineral absorption, bone mineral content, and bone structure. The Journal of Nutrition, 137(3), 838S–846S.
• Shang, Q., Liu, S., Liu, H., Mahfuz, S., & Piao, X. (2020). Impact of sugar beet pulp and wheat bran on serum biochemical profile, intestinal morphology, microbiota composition, and short-chain fatty acid concentration in rats. Journal of the Science of Food and Agriculture, 100(6), 2535–2544.
• Slavin, J. (2013). Fiber and prebiotics: mechanisms and health benefits. Nutrients, 5(4), 1417–1435.
• Smith, A. P., Sutherland, D., & Hewlett, P. (2015). An investigation of the acute effects of oligofructose-enriched inulin on subjective wellbeing, mood, and cognitive performance. Nutrients, 7(11), 8887–8896.
• Topping, D. L., & Clifton, P. M. (2001). Short-chain fatty acids and human colonic function. Physiological Reviews, 81(3), 1031–1064.
• Wilson, B., & Whelan, K. (2017). Prebiotic inulin-type fructans and galacto-oligosaccharides: definition, specificity, function, and application in gastrointestinal disorders. Gut, 66(11), 2053–2060.

Inulin is a naturally occurring soluble dietary fiber found in plants such as chicory root, onions, garlic, asparagus, and Jerusalem artichokes. It acts as a powerful prebiotic, selectively nourishing beneficial gut bacteria to support digestive health, immune function, and overall wellness. During fermentation in the gut, inulin produces short-chain fatty acids (SCFAs), which are linked to gut hormone pathways like GLP-1 that play a role in appetite and metabolic function*.

Scientifically Validated Health Benefits of Inulin:

• Digestive Health:
  Supports beneficial gut microbiota, particularly Bifidobacteria, promotes regularity, and helps maintain gut barrier function. May also help relieve occasional constipation (Slavin, 2013; Gibson et al., 2017).
• Immune Function:
  Supports balanced immune function through modulation of gut microbiota and gut-associated immune pathways (Lomax & Calder, 2009; Vandeputte et al., 2017).
• Weight Management:
  May help promote satiety and appetite regulation by influencing gut hormones such as GLP-1 and peptide YY, supporting healthy weight management (Cani et al., 2009; Parnell & Reimer, 2009).
• Cardiovascular Health:
  May support cardiovascular wellness by promoting healthy lipid metabolism, including reductions in LDL cholesterol and triglycerides, and supporting inflammatory balance (Brighenti, 2007; Dehghan et al., 2014).
• Skin Health:
  May support skin hydration, elasticity, and barrier function through effects on gut microbiota and inflammatory regulation, potentially benefiting the gut-skin axis (Salem et al., 2018; Kano et al., 2013).
• Athletic Recovery & Mineral Support:
  Supports absorption of key minerals like calcium and magnesium, and contributes to gut and immune health — factors linked to better physical recovery and resilience (Scholz-Ahrens et al., 2007; Cox et al., 2010).
• Brain & Mood Health:
  May help support mood and cognitive function through gut-brain axis signaling, microbial balance, and short-chain fatty acid production (Smith et al., 2015; Berding et al., 2021).
• Blood Sugar Support:
  May help maintain healthy blood sugar levels by supporting insulin sensitivity and glycemic balance (Guess et al., 2015; Wang et al., 2019).
• Bone Health & Mineral Absorption:
  Supports bone health by enhancing calcium and magnesium absorption — important for maintaining bone density and long-term skeletal wellness (Scholz-Ahrens et al., 2007; Abrams et al., 2007).
• Colorectal Health:
  May contribute to colorectal health by supporting microbiota diversity, gut barrier integrity, and SCFA production (Pool-Zobel & Sauer, 2005; Rafter et al., 2007).
  

Select References:

• Abrams, S. A., Griffin, I. J., Hawthorne, K. M., et al. (2007). A combination of prebiotic short- and long-chain inulin-type fructans enhances calcium absorption and bone mineralization in young adolescents. American Journal of Clinical Nutrition, 86(4), 1059–1064.
• Berding, K., Long-Smith, C. M., & Cryan, J. F. (2021). The microbiota-gut-brain axis in brain health and disease. Frontiers in Psychiatry, 12, 606634.
• Brighenti, F. (2007). Dietary fructans and serum triacylglycerols: meta-analysis of randomized trials. Journal of Nutrition, 137(11), 2552S–2556S.
• Cani, P. D., Lecourt, E., Dewulf, E. M., et al. (2009). Gut microbiota fermentation increases satiety hormones and glucose control. American Journal of Clinical Nutrition, 90(5), 1236–1243.
• Cox, A. J., Pyne, D. B., Saunders, P. U., & Fricker, P. A. (2010). Probiotics and mucosal immunity in endurance athletes. British Journal of Sports Medicine, 44(4), 222–226.
• Dehghan, P., Gargari, B. P., & Jafar-Abadi, M. A. (2014). Oligofructose-enriched inulin improves inflammatory markers in diabetes. Nutrition, 30(4), 418–423.
• Gibson, G. R., Hutkins, R., Sanders, M. E., et al. (2017). Consensus statement on prebiotics. Nature Reviews Gastroenterology & Hepatology, 14(8), 491–502.
• Guess, N. D., Dornhorst, A., Oliver, N., & Frost, G. S. (2015). A randomized controlled trial: inulin improves glycemic control. European Journal of Clinical Nutrition, 69(2), 162–167.
• Kano, M., Masuoka, N., Kaga, C., Sugimoto, S., & Iizuka, R. (2013). Consumption of prebiotic inulin beneficially impacts the skin condition of healthy adults. Functional Foods in Health and Disease, 3(9), 361–371.
• Lomax, A. R., & Calder, P. C. (2009). Prebiotics and immune function. British Journal of Nutrition, 101(5), 633–658.
• Parnell, J. A., & Reimer, R. A. (2009). Oligofructose supplementation reduces appetite and supports weight loss. American Journal of Clinical Nutrition, 89(6), 1751–1759.
• Pool-Zobel, B. L., & Sauer, J. (2005). Inulin-type fructans reduce colorectal cancer risk. British Journal of Nutrition, 93(S1), S73–S90.
• Rafter, J., Bennett, M., Caderni, G., et al. (2007). Dietary synbiotics reduce colon cancer risk factors. American Journal of Clinical Nutrition, 85(2), 488–496.
• Salem, I., Ramser, A., Isham, N., & Ghannoum, M. A. (2018). Gut microbiome and skin axis. Frontiers in Microbiology, 9, 1459.
• Scholz-Ahrens, K. E., Ade, P., Marten, B., et al. (2007). Prebiotics and bone mineralization. Journal of Nutrition, 137(3), 838S–846S.
• Slavin, J. (2013). Fiber and prebiotics: mechanisms and benefits. Nutrients, 5(4), 1417–1435.
• Smith, A. P., Sutherland, D., & Hewlett, P. (2015). Oligofructose-enriched inulin and cognitive function. Nutrients, 7(11), 8887–8896.
• Yamashita, K., Kawai, K., Itagaki, S., et al. (2018). Effects of inulin and phytosterol-enriched soymilk on GLP-1 secretion in healthy men. BMC Research Notes, 11, 774.
• Vandeputte, D., Falony, G., Vieira-Silva, S., et al. (2017). Prebiotic inulin modulates gut microbiota and immune markers. Gut, 66(11), 1968–1974.
• Wang, L., Yang, H., Huang, H., et al. (2019). Inulin improves type 2 diabetes. European Journal of Clinical Nutrition, 73(2), 272–279.

Isomalto-oligosaccharides (IMOs) are soluble prebiotic fibers derived from plant sources like tapioca, known for supporting gut health and overall wellness. These short-chain carbohydrates resist digestion in the small intestine and reach the colon, where they selectively nourish beneficial gut bacteria. This fermentation process promotes the production of short-chain fatty acids (SCFAs), which are associated with gut hormone pathways such as GLP-1 and support digestive health, healthy metabolism, and immune system balance*.

Scientifically Studied Health Benefits of Isomalto-Oligosaccharides (IMOs)

• Digestive Health:
  Selectively support beneficial gut bacteria, such as Bifidobacteria, and help promote microbiota diversity, gut barrier integrity, and digestive comfort (Gibson et al., 2017; Carlson et al., 2018).
• Immune Function:
  Support immune health by helping maintain gut microbial balance and interacting with gut-associated lymphoid tissue (GALT), which plays a role in immune signaling and resilience (Lomax & Calder, 2009; Xiao et al., 2020).
• Weight Management & Metabolic Health:
  May support appetite regulation, glucose balance, and healthy weight management through prebiotic fermentation and gut hormone signaling, including GLP-1 activity (Carlson et al., 2018; Cani et al., 2009).
• Brain & Mood Health:
  May support emotional well-being and cognitive function through gut-brain axis pathways, microbial modulation, and short-chain fatty acid (SCFA) production (Berding et al., 2021; Cryan et al., 2019).
• Cardiovascular Health:
  May support cardiovascular health by influencing lipid metabolism, glucose regulation, and inflammatory balance through microbiota modulation and SCFA production (Brighenti, 2007; Carlson et al., 2018).
• Athletic Recovery & Gut Comfort:
  May help improve nutrient absorption, digestive resilience, and immune function—factors that support consistent training and post-exercise recovery (Cox et al., 2010; Carlson et al., 2018).
• Microbial Balance & Pathogen Defense:
  Support a healthy microbial environment that may help limit pathogen adhesion and promote gut ecosystem stability (Xiao et al., 2020; Gibson et al., 2017).
• Colorectal Health & Gut Integrity:
  May contribute to gut barrier support, microbiota diversity, and SCFA activity—factors associated with long-term colon health (Pool-Zobel & Sauer, 2005; Carlson et al., 2018).
• Blood Sugar Support:
  May promote healthy glucose metabolism and insulin sensitivity, supporting blood sugar balance as part of a health-conscious lifestyle (Carlson et al., 2018; Respondek et al., 2011).

Select References:

• Berding, K., Long-Smith, C. M., & Cryan, J. F. (2021). The microbiota-gut-brain axis in brain health and disease. Frontiers in Psychiatry, 12, 606634.
• Brighenti, F. (2007). Dietary fructans and serum triacylglycerols: a meta-analysis of randomized controlled trials. Journal of Nutrition, 137(11), 2552S–2556S.
• Carlson, J. L., Erickson, J. M., Lloyd, B. B., & Slavin, J. L. (2018). Health effects and sources of prebiotic dietary fiber. Current Developments in Nutrition, 2(3), nzy005.
• Cani, P. D., Lecourt, E., Dewulf, E. M., et al. (2009). Gut microbiota fermentation of prebiotics increases satiety and gut peptide production with consequences for appetite and glucose response. The American Journal of Clinical Nutrition, 90(5), 1236–1243.
• Cox, A. J., Pyne, D. B., Saunders, P. U., & Fricker, P. A. (2010). Oral probiotics and mucosal immunity in endurance athletes. British Journal of Sports Medicine, 44(4), 222–226.
• Cryan, J. F., O'Riordan, K. J., Cowan, C. S., et al. (2019). The microbiota-gut-brain axis. Physiological Reviews, 99(4), 1877–2013.
• Gibson, G. R., Hutkins, R., Sanders, M. E., et al. (2017). Expert consensus document: ISAPP consensus statement on prebiotics. Nature Reviews Gastroenterology & Hepatology, 14(8), 491–502.
• Lomax, A. R., & Calder, P. C. (2009). Prebiotics, immune function, infection, and inflammation. British Journal of Nutrition, 101(5), 633–658.
• Pool-Zobel, B. L., & Sauer, J. (2005). Reduction of colorectal cancer risk by inulin-type fructans. British Journal of Nutrition, 93(S1), S73–S90.
• Respondek, F., Swanson, K. S., et al. (2011). Short-chain fructooligosaccharides influence insulin sensitivity and gene expression in obese dogs. Journal of Nutrition, 141(10), 1712–1718.
• Xiao, L., Engen, P. A., et al. (2020). Prebiotic modulation of gut microbiota improves inflammation and infection outcomes. Critical Reviews in Food Science and Nutrition, 60(9), 1429–1444.

Tapioca fiber, extracted from cassava root, is a soluble dietary fiber known for its prebiotic properties and versatile health benefits. It selectively nourishes beneficial gut bacteria, supporting digestive health, metabolic balance, and overall wellness. Regular consumption may enhance gut microbiota diversity and promote the production of beneficial short-chain fatty acids (SCFAs), which are associated with gut hormone pathways like GLP-1—known to play a role in appetite and metabolic function. These effects contribute to digestive comfort and whole-body balance*.

Scientifically Studied Health Benefits of Tapioca Fiber

• Digestive Health (Prebiotic Effect):
  Supports beneficial gut bacteria like Bifidobacteria, promotes bowel regularity, and helps maintain gut microbiota balance and digestive comfort (Carlson et al., 2018; Slavin, 2013).
• Immune Function:
  May support immune health by promoting gut microbial balance and gut barrier integrity, which help maintain immune resilience (Lomax & Calder, 2009; Carlson et al., 2018).
• Weight Management & Satiety:
  May help promote feelings of fullness and satiety by influencing GLP-1 and other gut hormones, supporting appetite regulation and weight management (Slavin, 2013; Wanders et al., 2011; Cani et al., 2009).
• Cardiovascular Health (Cholesterol Management):
  May support cardiovascular wellness by promoting healthy cholesterol metabolism and lipid balance, aided by its soluble fiber content (Brown et al., 1999; Carlson et al., 2018).
• Blood Sugar Support:
  May help maintain healthy blood sugar levels and insulin sensitivity by slowing glucose absorption and supporting metabolic balance (Slavin, 2013; Wanders et al., 2011).
• Colon Health & Regularity:
  Promotes digestive regularity, helps increase stool bulk, and may contribute to long-term colon health by supporting microbial balance and SCFA production (Carlson et al., 2018; Slavin, 2013).
• Athletic Recovery & Resilience:
  May support recovery and training consistency by promoting nutrient absorption, digestive health, and immune function—key factors in physical performance (Carlson et al., 2018; Cox et al., 2010).
• Gluten-Free & Digestive-Friendly Option:
  Offers a gluten-free, well-tolerated fiber source suitable for people with gluten sensitivity, wheat allergy, or celiac needs, adding nutritional variety to restricted diets (Thompson, 2000).
• Supports Mineral Absorption:
  Helps support absorption of key minerals like calcium and magnesium by promoting SCFA production and microbiome health (Scholz-Ahrens et al., 2007; Carlson et al., 2018).
  

Select References:

• Brown, L., Rosner, B., Willett, W. W., & Sacks, F. M. (1999). Cholesterol-lowering effects of dietary fiber: A meta-analysis. American Journal of Clinical Nutrition, 69(1), 30–42.
• Cani, P. D., Lecourt, E., Dewulf, E. M., et al. (2009). Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal. The American Journal of Clinical Nutrition, 90(5), 1236–1243.
• Carlson, J. L., Erickson, J. M., Lloyd, B. B., & Slavin, J. L. (2018). Health effects and sources of prebiotic dietary fiber. Current Developments in Nutrition, 2(3), nzy005.
• Cox, A. J., Pyne, D. B., Saunders, P. U., & Fricker, P. A. (2010). Probiotics and mucosal immunity in endurance athletes. British Journal of Sports Medicine, 44(4), 222–226.
• Lomax, A. R., & Calder, P. C. (2009). Prebiotics, immune function, infection, and inflammation. British Journal of Nutrition, 101(5), 633–658.
• Scholz-Ahrens, K. E., Ade, P., Marten, B., et al. (2007). Prebiotics, probiotics, and mineral absorption. Journal of Nutrition, 137(3), 838S–846S.
• Slavin, J. (2013). Fiber and prebiotics: mechanisms and health benefits. Nutrients, 5(4), 1417–1435.
• Thompson, T. (2000). Folate, iron, and dietary fiber contents of the gluten-free diet. Journal of the American Dietetic Association, 100(11), 1389–1396.
• Wanders, A. J., van den Borne, J. J. G. C., de Graaf, C., et al. (2011). Effects of dietary fibre on subjective appetite, energy intake and body weight: a systematic review. Obesity Reviews, 12(9), 724–739.

Allulose is a science-backed prebiotic sweetener that supports gut, metabolic, and overall wellness. It selectively nourishes beneficial gut bacteria, promotes short-chain fatty acid (SCFA) production, aids digestion, helps curb sugar impact, and supports healthy weight management by promoting appetite control and metabolic balance*. Its role in energy metabolism and recovery also makes it a smart choice for active individuals and athletes seeking whole-body support*. Emerging research links allulose to gut hormone pathways such as GLP-1, which are associated with appetite regulation and energy utilization*.

Scientifically Studied Health Benefits of Allulose

• Digestive Health (Prebiotic Effect):
  Supports digestive health by nourishing beneficial gut bacteria, promoting short-chain fatty acid (SCFA) production, and contributing to gut integrity and comfort (Iida et al., 2010; Nishida et al., 2020).
• Weight Management & Body Composition:
  May support healthy weight management and reductions in visceral and body fat, potentially by influencing gut hormone pathways such as GLP-1, which are involved in satiety and metabolic balance (Han et al., 2018; Kimura et al., 2017).
• Athletic Recovery & Endurance:
  Emerging research suggests allulose may help support endurance, glycogen replenishment, and post-exercise recovery, though more studies are needed to confirm performance effects (Tsuzuki et al., 2022; Liu et al., 2022).
• Antioxidant & Inflammatory Balance:
  Demonstrates antioxidant activity and may help support a balanced inflammatory response (Braunstein et al., 2023; Hossain et al., 2015).
• Metabolic Health & Insulin Sensitivity:
  May help support insulin sensitivity and metabolic health by contributing to glucose and fat metabolism (Han et al., 2018; Nishida et al., 2020).
• Cardiovascular Support:
  May support heart health by promoting healthy lipid metabolism, body composition, and glycemic control (Han et al., 2018; Braunstein et al., 2023).
• Blood Sugar Support:
  May help reduce post-meal glucose spikes by modulating carbohydrate absorption, supporting healthy blood sugar levels (Noda et al., 2018; Braunstein et al., 2023).
• Dental Health:
  Offers sweetness without promoting tooth decay, as allulose is not fermented by oral bacteria (Matsuo et al., 2002; FDA, 2019).
• Liver Health:
  May help support liver health by promoting healthy fat metabolism and limiting excess fat accumulation (Han et al., 2018; Itoh et al., 2015).
  

Why Is Allulose Considered "Sugar-Free"?

Although allulose is chemically classified as a sugar, the FDA recognizes it as metabolically distinct. It contributes just 0.4 calories per gram, has minimal impact on blood glucose or insulin, and is not counted toward “total sugars” or “added sugars” on nutrition labels. As a result, the FDA allows allulose to be labeled as sugar-free when meeting all regulatory requirements (FDA, 2019).

Select References:

• Braunstein, C. R., Noronha, J. C., Khan, T. A., et al. (2023). Effects of Allulose on Glycemic Control. Nutrients, 15(12), 2802.
• FDA. (2019). The Declaration of Allulose and Calories from Allulose on Nutrition and Supplement Facts Labels. U.S. Food and Drug Administration.
• Han, Y., Kwon, E. Y., Choi, M. S. (2018). Anti-diabetic and Anti-obesity Effects of Allulose in Diet-induced Obese Mice. Nutrients, 10(2), 201.
• Hossain, M. A., Kitagaki, S., Nakano, D., et al. (2015). Rare sugar D-psicose improves insulin sensitivity and reduces oxidative stress. Journal of Food Science, 80(7), H1619–H1626.
• Iida, T., Kishimoto, Y., Yoshikawa, Y., et al. (2010). Estimation of Maximum Non-Effective Level of D-psicose in Causing Diarrhea in Humans. Journal of Advances in Food Ingredients, 13, 12–18.
• Itoh, K., Mizuno, S., Hama, S., et al. (2015). Beneficial effects of supplementation of rare sugar D-allulose against hepatic steatosis in mice. Journal of Functional Foods, 14, 680–687.
• Kimura, T., Kanasaki, A., Hayashi, N., et al. (2017). Dietary D-allulose alters glucose metabolism and adiposity in healthy and obese individuals. Journal of Food Science, 82(7), 1616–1622.
• Liu, B., Gou, Y., Tsuzuki, T., et al. (2022). D-Allulose Improves Endurance and Recovery from Exhaustion in Male C57BL/6J Mice. Nutrients, 14(5), 1026.
• Matsuo, T., Tanaka, T., Hashiguchi, M., & Izumori, K. (2002). Dietary D-psicose does not contribute to tooth decay. Journal of Clinical Biochemistry and Nutrition, 32, 55–63.
• Nishida, Y., Nakaishi, S., & Nakamura, Y. (2020). Allulose and metabolic syndrome: a review. Foods, 9(8), 1014.
• Noda, K., Oh, T., Yoshida, M., et al. (2018). Effects of D-allulose on glucose tolerance and glycemic response. Journal of Functional Foods, 49, 237–243.
• Tsuzuki, T., Suzuki, R., Kajun, R., et al. (2022). Combined effects of exercise training and D‐allulose intake on endurance capacity in mice. Physiological Reports, 10(8), e15297.

Pectin is a natural, soluble dietary fiber found in apples, citrus fruits, pears, and berries. Known for its prebiotic properties, pectin supports digestive health by selectively nourishing beneficial gut bacteria, helping maintain gut barrier integrity, and promoting the production of short-chain fatty acids (SCFAs). These SCFAs are linked to gut hormone pathways such as GLP-1, which are associated with appetite regulation and metabolic function*. Regular consumption of pectin supports digestive comfort, immune health, cardiovascular wellness, weight management, and cognitive and emotional balance as part of overall wellness*.

Scientifically Studied Health Benefits of Pectin

• Digestive Health (Prebiotic Effect):
  Supports beneficial gut bacteria, promotes regularity, and may help relieve occasional constipation and digestive discomfort (Slavin, 2013; Holscher, 2017).
• Immune Function:
  Supports balanced immune function by promoting gut barrier health and microbial balance, both of which play a role in immune regulation (Vogt et al., 2016; Lomax & Calder, 2009).
• Weight Management & Satiety:
  May help promote feelings of fullness and appetite regulation by supporting GLP-1 activity, a gut hormone involved in satiety and energy intake (Wanders et al., 2011; Adam et al., 2015; Cani et al., 2009).
• Cardiovascular Health & Cholesterol Support:
  May help support cardiovascular wellness by promoting healthy cholesterol metabolism and lipid balance (Brown et al., 1999; Brouns et al., 2012).
• Blood Sugar Support:
  May help maintain healthy post-meal blood sugar levels and support insulin sensitivity (Dongowski et al., 2002; Brouns et al., 2012).
• Colon & Gut Health:
  Supports colon health by promoting microbial diversity, reinforcing gut barrier function, and contributing to overall digestive wellness (Holscher, 2017; Brouns et al., 2012).
• Athletic Recovery & Resilience:
  May support physical recovery and immune resilience by promoting nutrient absorption and gut health—key factors for maintaining training consistency (Cox et al., 2010; Carlson et al., 2018).
• Skin Health & Hydration:
  May support skin elasticity, hydration, and appearance by promoting gut balance and inflammatory regulation through the gut-skin axis (Mesbahzadeh et al., 2020; Salem et al., 2018).
• Brain & Mood Health:
  May help support emotional well-being, mood, and cognitive function by influencing the gut-brain axis and gut-driven inflammatory balance (Berding et al., 2021; Cryan et al., 2019).
• Gut-Supported Detoxification:
  Pectin may bind certain heavy metals in the digestive tract, supporting natural elimination through the gut—a function tied to its soluble fiber content (Eliaz et al., 2006; Zhao et al., 2008).
  

Select References:

• Adam, C. L., Thomson, L. M., Williams, P. A., & Ross, A. W. (2015). Soluble dietary fibre (pectin) reduces adiposity. PLoS One, 10(10), e0140392.
• Berding, K., Long-Smith, C. M., & Cryan, J. F. (2021). The microbiota-gut-brain axis in brain health and disease. Frontiers in Psychiatry, 12, 606634.
• Brouns, F., Theuwissen, E., Adam, A., et al. (2012). Cholesterol-lowering properties of pectin. Clinical Reviews in Food Science and Nutrition, 52(2), 125–147.
• Brown, L., Rosner, B., Willett, W. W., & Sacks, F. M. (1999). Cholesterol-lowering effects of dietary fiber: meta-analysis. American Journal of Clinical Nutrition, 69(1), 30–42.
• Cani, P. D., Lecourt, E., Dewulf, E. M., et al. (2009). Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal. The American Journal of Clinical Nutrition, 90(5), 1236–1243.
• Carlson, J. L., Erickson, J. M., Lloyd, B. B., & Slavin, J. L. (2018). Health effects of prebiotic dietary fiber. Current Developments in Nutrition, 2(3), nzy005.
• Cox, A. J., Pyne, D. B., Saunders, P. U., & Fricker, P. A. (2010). Probiotics and mucosal immunity in endurance athletes. British Journal of Sports Medicine, 44(4), 222–226.
• Cryan, J. F., O'Riordan, K. J., Cowan, C. S., et al. (2019). The microbiota-gut-brain axis. Physiological Reviews, 99(4), 1877–2013.
• Dongowski, G., Lorenz, A., & Proll, J. (2002). Pectin reduces glucose absorption. Journal of Nutrition, 132(11), 3602–3607.
• Eliaz, I., Hotchkiss, A. T., Fishman, M. L., & Rode, D. (2006). Modified citrus pectin inhibits metastasis and chelates heavy metals. Alternative Therapies in Health and Medicine, 12(3), 34–38.
• Holscher, H. D. (2017). Dietary fiber, prebiotics, and gastrointestinal microbiota. Gut Microbes, 8(2), 172–184.
• Lomax, A. R., & Calder, P. C. (2009). Prebiotics, immune function, infection, and inflammation. British Journal of Nutrition, 101(5), 633–658.
• Mesbahzadeh, B., Akbarzadeh, M., & Ghahremani, L. (2020). Citrus pectin improves skin hydration and elasticity. Journal of Cosmetic Dermatology, 19(11), 2946–2951.
• Salem, I., Ramser, A., Isham, N., & Ghannoum, M. A. (2018). Gut microbiome as regulator of the gut-skin axis. Frontiers in Microbiology, 9, 1459.
• Slavin, J. (2013). Fiber and prebiotics: mechanisms and health benefits. Nutrients, 5(4), 1417–1435.
• Vogt, L. M., Meyer, D., Pullens, G., et al. (2016). Immunological properties of inulin-type fructans and pectins. Critical Reviews in Food Science and Nutrition, 56(9), 1497–1513.
• Wanders, A. J., van den Borne, J. J. G. C., de Graaf, C., et al. (2011). Dietary fibre effects on appetite, energy intake, and body weight. Obesity Reviews, 12(9), 724–739.
• Zhao, Z. Y., Liang, L., Fan, X., et al. (2008). Pectin detoxifies heavy metals from human blood. Environmental Toxicology and Pharmacology, 26(2), 225–231.